Tupelo is a city in, and the county seat of, Lee County, Mississippi, United States. With an estimated population of 38,312 in 2019, Tupelo is the sixth-largest city in Mississippi and is considered a commercial, industrial, and cultural hub of North Mississippi. Tupelo was incorporated in 1866, although the area had earlier been settled as "Gum Pond" along the Mobile and Ohio Railroad. On February 7, 1934, Tupelo became the first city to receive... Show more

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